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Biorise

Bioavailability Enhancement

Our two proprietary activation systems break down drug particles to their thermodynamically activated form to increase solubility profiles.

Creating new physical entities

How it works

Key drug characteristics are reviewed and either a high-energy mechano-chemical activation (HEMA) or a solvent-induced activation (SIA) system is selected. The processes convert drugs to their thermodynamically activated state, which increases solubility.

These systems create new physical entities by breaking down the crystalline drug into nanocrystals and/or amorphous (non-crystalline) particles. It is then stabilized in a carrier system to maintain the drug in its activated form throughout its shelf life.

Key advantages

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