A solid-solution/solid dispersion drug form is contained in layers of excipients and release-controlling polymers. This is combined with a crystallization inhibitor, enhancing bioavailability by maintaining the drug in its amorphous state. The solubility-enhanced beads can be coated with one or more functional polymers to achieve extended-release profiles suitable for once- or twice-daily dosing.
Solid-Solution or Solid-Dispersion
An alternative to our standard Diffucaps® system, Solid-Solution or Solid-Dispersion Diffucaps® enhance bioavailability by preserving a drug’s amorphous form. Additional functional polymers can achieve extended release profiles.