The bioavailability of a drug is strongly dependent on its solubility in the aqueous environment of the gastrointestinal tract. Solubility is one key determinant among several biopharmaceutical properties that influence the speed of onset of action, the variability of absorption between patients, and any food effect variation.
Our two distinct, patented, proprietary technologies—BioriseTM and Diffucaps® (Solid-Solution or Solid-Dispersion)—enhance bioavailability of drugs that are poorly soluble at physiological pHs.
In addition, we have the capacity to apply hot-melt extrusion (HME) and spray-drying techniques to enhance solubility.
Learn more about our bioavailability enhancement technologies: