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Customized Drug Release

MMTSTM Multi Mini Tablet System Controlled Release Technology

Precise dosing, delivered in a wide range of patient-centric formulations

This technology combines the simplicity of a tablet formulation with the flexibility of multiparticulate dosage forms with high drug-loading capability.

Adare has developed Ultra Microtablets—a smaller standard of tablets targeting diameters in the range of 1.2 mm to even 1.0 mm. With this latest innovation, Adare now offers a range of multiparticulate dosage forms that provide precision dosing through smaller dosage strengths.

Eurand Minitabs® can be loaded into capsules for flexible dosing

How MMTSTM Controlled Release Technology works

Tiny cylindrical tablets (1.0 mm-2.0 mm in diameter) are created and functional membranes are applied to further control release rates. Because of their small sizes, these tablets can be filled into capsules or sachets as final dosage forms. This facilitates the development of combination products that offer two or more drugs or release profiles within a single capsule. MMTSTM technology can also utilize Diffutab® Customized Release Technology, allowing for even greater flexibility in designing a release profile. A significant advantage of MMTSTM technology is the ability for the patient or caregiver to open the capsule and sprinkle the contents on soft foods or add to a liquid. This is especially helpful for the pediatric patient, the elderly patient, or anyone who has difficulty swallowing.

MMTS™ can be loaded into capsules for flexible dosing.

Advantages of MMTSTM technology

  • Combination tablet and multiparticulate dosage form that offers flexible dose delivery (capsules, sachets, sprinkles), which may improve adherence
  • Provides a range of tablet sizes, improving ease of administration for patients who experience swallowing difficulties, including pediatric, geriatric, and dysphagic patients
    • Microtablets and Ultra Microtablets allow for more precise delivery of medication at lower dosage strengths
  • Allows for a wide range of customized release profiles within a single capsule
  • High drug-loading capability with the possibility to combine with a high-density formulation that is particularly attractive for high-strength formulations
  • Titration of a broader range of dosages, including smaller dosage strengths